Chemistry - A European Journal · 2015 · 11 citations · 53 references
Life SciencesBiochemistryMolecular BiologyBiosensorsMolecular ImagingSensorsBiological SensorsCell-surface ReceptorsLigand BindingMolecular SensorsProtein-ligand BindingReceptor-ligand InteractionsBinder SelectionCalmodulin-dependent Protein Kinase IiCalmodulin-mediated RegulationCell Surface Receptor BiosensorsCell Surface Recognition ReceptorsCell-surface Protein LabelingFluorescent Molecular SensorsFluorescent Sensors
Invited for the cover of this issue is the group of David Margulies at the Weizmann Institute of Science (Israel). The image highlights the analogy between fluorescent molecular sensors and a miniaturized camera that can capture changes that occur at the nanoscale and shed light on the structural state of proteins. Read the full text of the article at 10.1002/chem.201502069.
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In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations
Medicine, Oncology, Pharmacology +15
Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix
Loren D. Walensky, Andrew L. Kung, Iris Escher et al. · Science · 2004 · 1.3K citations · Full text