The endocannabinoid system in renal cells: regulation of<scp><scp>Na</scp></scp>⁺transport by<scp>CB</scp>₁receptors through distinct cell signalling pathways

Abstract

The ECS is expressed in LLC-PK1 cells. Both CB1 receptors and TRPV1 channels regulate Na(+) /K(+) -ATPase activity in these cells, and are modulated by lipid and peptide CB1 receptor ligands, which act via different signalling pathways.