Allele Frequency and Genotype Distribution of Polymorphisms within Disease-Related Genes is Influenced by Ethnic Population Sub-Structuring in Sudan

Linkage disequilibrium in the human genome

David Reich, Michele Cargill, Stacey Bolk et al. · Nature · 2001 · 1.8K citations

Linkage Disequilibrium, Genetics, Linkage Analysis +5

Role of a p53 polymorphism in the development of human papilloma-virus-associated cancer

Alan Storey, Miranda Thomas, Ann Kalita et al. · Nature · 1998 · 980 citations

Tumor Biology, P53 Polymorphism, Oncology +9

Single base polymorphism in the human Tumour Necrosis Factor alpha (TNFα) gene detectable by <i>Ncol</i> restriction of PCR product

AG Wilson, Francesco S. di Giovine, Alexandra I. F. Blakemore et al. · Human Molecular Genetics · 1992 · 892 citations

Genetics, Immunology, Human Polymorphism +18

dbSNP: a database of single nucleotide polymorphisms

Elizabeth M. Smigielski · Nucleic Acids Research · 2000 · 630 citations · Full text

Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production.

Gerald Messer, Ulrich Spengler, M. Jung et al. · The Journal of Experimental Medicine · 1991 · 548 citations · Full text

Immunology, Immune Regulation, Cell Death +18