The HL‐A System in Lymphoblastic Leukaemia

Abstract

S ummary The HL‐A system was studied in 58 Caucasian patients with acute lymphoblastic leukaemia and their available close relatives. No gross disturbance in the distribution of the internationally defined antigens was found in the patients or their families. The high frequency of the FJH antigen is discussed. Segregation ratios within the families were, as expected, on a random basis. The haplotypes occurring most frequently in the patients were those found also to be commonest in the normal population. Suceptibility to aute lymphoblastic leukaemia could thus not be related to any particular HL‐A phenotype or genotype.