Clinical Endocrinology · 1999 · 100 citations · 38 references
Serum leptin concentrations rose slightly during pregnancy, fell following delivery and subsequently increased during the first six months postpartum. These variations were unrelated to changes in body composition, and may be responsible for the postpartum weight gain observed in some women. Abnormally low serum leptin levels were observed in women suffering spontaneous abortion in the first trimester of pregnancy.
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Positional cloning of the mouse obese gene and its human homologue
Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.3K citations
Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene
Jeffrey L. Halaas, K.S. Gajiwala, Margherita Maffei et al. · Science · 1995 · 4.4K citations