Optimization of ultrasound-assisted extraction (UAE) of phenolic compounds from Crataegus pinnatifida leaves and evaluation of antioxidant activities of extracts

Abstract

In this study, a highly efficient BBD–RSM optimized ultrasound-assisted extraction combined with HPLC method has been established for the simultaneous extraction and determination of CA, VG, VR, ORT, RT, VIT and HYP from <italic>Crataegus pinnatifida</italic> leaves.