Concepedia

Publication | Open Access

MAP3K11/GDF15 axis is a critical driver of cancer cachexia

DOIFull Paper Access

174

Citations

40

References

2015

Year

Lorena Lerner, Julie Tao, Qing Liu, Richard Nicoletti, Bin Feng, Brian Krieger, Elizabeth K. Mazsa, Zakir Siddiquee, Ruoji Wang, Lucia Huang,
Journal of Cachexia Sarcopenia and Muscle

Abstract

The combination of correlative observations, gain of function, and loss of function experiments validated GDF15 as a key driver of cancer cachexia and as a potential therapeutic target for the treatment and/or prevention of this syndrome.

References

YearCitations

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