Mammalian target of rapamycin complex 1 (mTORC1) Is required for mouse spermatogonial differentiation in vivo

Global quantification of mammalian gene expression control

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Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

Anne Brunet, Azad Bonni, Michael J. Zigmond et al. · Cell · 1999 · 6.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

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Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation

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Medicine, Oncology, Pathology +10

Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

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Life Sciences, Molecular Biology, Pharmacology +6