PEG-assisted two-component approach for the facile synthesis of 5-aryl-1,2,4-triazolidine-3-thiones under catalyst-free conditions

Abstract

A straightforward and greener PEG-assisted protocol has been disclosed for the synthesis of 5-aryl-1,2,4-triazolidine-3-thiones <italic>via</italic> the reaction of aromatic aldehydes and thiosemicarbazides using very convenient neutral reaction conditions.