Concepedia

Pathophysiology of essential hypertension: Role of the pump, the vessel, and the kidney

Ashley E. Cain, Raouf A. Khalil

Seminars in Nephrology · 2002 · 70 citations · 88 references

DOI

Concepts

References

88

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

Masashi Yanagisawa, Hiroki Kurihara, Sadao Kimura et al. · Nature · 1988 · 10.8K citations · Full text

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Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

L J Ignarro, Georgette M. Buga, K S Wood et al. · Proceedings of the National Academy of Sciences · 1987 · 5.1K citations · Full text

, , +12

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

Masayoshi Uehata, Toshimasa Ishizaki, Hiroyuki Satoh et al. · Nature · 1997 · 2.9K citations

, , +16

Abnormal Endothelium-Dependent Vascular Relaxation in Patients with Essential Hypertension

Julio A. Panza, Arshed A. Quyyumi, John E. Brush et al. · New England Journal of Medicine · 1990 · 2.4K citations · Full text

, , +15

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

Paul L. Huang, Zhihong Huang, Hiroshi Mashimo et al. · Nature · 1995 · 2.1K citations

, , +12