Concepedia

Publication | Open Access

Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes

DOIFull Paper Access

147

Citations

35

References

2015

Year

Tao Xu, Stefan Brandmaier, Ana C. Messias, Christian Herder, Harmen H. M. Draisma, Ayşe Demirkan, Zhonghao Yu, Janina S. Ried, Toomas Haller, Margit Heier,
Diabetes Care

Abstract

Our results indicate that metformin intake activates AMPK and consequently suppresses FADS, which leads to reduced levels of the three acyl-alkyl PCs and LDL-C. Our findings suggest potential beneficial effects of metformin in the prevention of cardiovascular disease.

References

YearCitations

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