Common features and differences in the transcriptome of large cell anaplastic lymphoma and classical Hodgkin's lymphoma.

Abstract

At a transcriptional level HL is more closely related to Alk+ ALCL than to the B-NHL or B-cell samples investigated, although it is a B-cell derived lymphoma. The newly identified genes discriminating HL and ALCL may be pathobiologically important and may serve as possible therapeutic targets.