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Publication | Open Access

Integrated semi‐physiological pharmacokinetic model for both sunitinib and its active metabolite <scp>SU</scp>12662

DOIFull Paper Access

32

Citations

34

References

2014

Year

Huixin Yu, Neeltje Steeghs, Jacqueline S. L. Kloth, Djoeke de Wit, J. G. Coen van Hasselt, Nielka P. van Erp, Jos H. Beijnen, Jan H.M. Schellens, Ron H.J. Mathijssen, Alwin D. R. Huitema
British Journal of Clinical Pharmacology

Abstract

A semi-physiological PK model for sunitinib and SU12662 in cancer patients was presented including pre-systemic metabolism. The model was superior to previous PK models in many aspects.

References

YearCitations

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