Concepedia

Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis

Xinran Ma, Lingyan Xu, Anna Teresa Alberobello, Oksana Gavrilova, Alessia Bagattin, Monica C. Skarulis, Jie Liu, Toren Finkel, Elisabetta Mueller

Cell Metabolism · 2015 · 356 citations · 45 references

DOIFull text

Open access

Concepts

References

45

Identification and Importance of Brown Adipose Tissue in Adult Humans

Aaron M. Cypess, Sanaz Lehman, Gethin Williams et al. · New England Journal of Medicine · 2009 · 4.4K citations · Full text

, , +15

Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

Zhidan Wu, Pere Puigserver, Chen‐Yu Zhang et al. · Cell · 1999 · 4.1K citations · Full text

, , +14

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Marie Lagouge, Carmen Argmann, Zachary Gerhart‐Hines et al. · Cell · 2006 · 4K citations · Full text

, , +16

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Jun Wu, Pontus Boström, Lauren M. Sparks et al. · Cell · 2012 · 3.3K citations · Full text

, , +14

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

Jiandie D. Lin, Paul T. Tarr, Chen-Yu Zhang et al. · Nature · 2002 · 2.5K citations

, , +13