Hybrid Pharmacokinetic Models to Describe Anti-HIV Nucleoside Brain Disposition Following Parent and Prodrug Administration in Mice

Respiration and Circulation.

Annals of Internal Medicine · 1971 · 467 citations

Life Sciences, Physiology, Zoology +16

3′-azido-3′-deoxythymidine. An unusual nucleoside analogue that permeates the membrane of human erythrocytes and lymphocytes by nonfacilitated diffusion.

Thomas P. Zimmerman, William B. Mahony, Karen Prus · Journal of Biological Chemistry · 1987 · 224 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16

The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3′-azido-2′,3′-dideoxythymidine and 2′,3′-dideoxycytidine are highly dependent on the cell species

Jan Balzarini, Rudi Pauwels, Masanori Baba et al. · Biochemical Pharmacology · 1988 · 185 citations

Life Sciences, Biochemistry, Molecular Biology +9

Measurement of the distribution of cardiac output in unanesthetized rats

Yasunobu Sasaki, H N Wagner · Journal of Applied Physiology · 1971 · 149 citations

Life Sciences, Cardiology, Physiology +7

Distributed model for drug delivery to CSF and brain tissue

John M. Collins, Robert L. Dedrick · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1983 · 108 citations

Pharmacy, Pharmacokinetics, Pharmacology +17