Concepedia

Risk factors that predict the requirement of aggressive therapy among Chinese patients with Crohn's disease

Chuan Hua Yang, Juan Ding, Yan Gao, Xiang Chen, Zhao Yang, Shu Dong XIAO

Journal of Digestive Diseases · 2011 · 30 citations · 29 references

DOIFull text

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Abstract

The risk factors associated with disabling Crohn's disease, which entails the requirement of top-down therapy in Chinese patients, are requirement of steroids for treating acute exacerbation and the presence of perianal disease at diagnosis.

References

29

Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial

Stephen B. Hanauer, Brian G. Feagan, Gary R. Lichtenstein et al. · The Lancet · 2002 · 4.1K citations

, , +5

Tuberculosis Associated with Infliximab, a Tumor Necrosis Factor α–Neutralizing Agent

Joseph Keane, Sharon K. Gershon, Robert P. Wise et al. · New England Journal of Medicine · 2001 · 3.7K citations · Full text

Infliximab for the Treatment of Fistulas in Patients with Crohn's Disease

Daniel H. Present, Paul Rutgeerts, Stephan Targan et al. · New England Journal of Medicine · 1999 · 2.7K citations · Full text

The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis

Gert Van Assche, Julián Panés, Laurent Beaugerie et al. · Journal of Crohn s and Colitis · 2010 · 1.5K citations · Full text

Treatment of Crohn's Disease with 6-Mercaptopurine

Daniel H. Present, Burton I. Korelitz, Nathaniel Wisch et al. · New England Journal of Medicine · 1980 · 1K citations

, , +7