Concepedia

Step-up Therapy

Step-Up Therapy is a clinical management strategy within the domain of Combination Inhaler Therapy that involves escalating the intensity or complexity of treatment by adding or increasing the dose of pharmacological agents to achieve better disease control when initial therapy proves insufficient.

74

Publications

6.3K

Citations

593

Authors

282

Institutions

Publications per year

2017–2026

22

Parents

Publications

74

Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): A randomized, controlled trial

Y P M Goekoop-Ruiterman, Jeska K de Vries‐Bouwstra, Cornelia F Allaart et al. · Arthritis & Rheumatism · 2005 · 1.5K citations · Full text

, , +14

Comparison of treatment strategies in early rheumatoid arthritis: a randomized trial.

Yvonne P M Goekoop-Ruiterman · PubMed · 2007 · 448 citations

, , +15

Step-up Therapy for Children with Uncontrolled Asthma Receiving Inhaled Corticosteroids

Robert F. Lemanske, David T. Mauger, Christine A. Sorkness et al. · New England Journal of Medicine · 2010 · 444 citations · Full text

, , +16

A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: The Treatment of Early Aggressive Rheumatoid Arthritis trial

Larry W. Moreland, James R. O’Dell, Harold E. Paulus et al. · Arthritis & Rheumatism · 2012 · 388 citations

, , +16

A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial

Nurulamin M Noor, James Lee, Simon Bond et al. · ˜The œLancet. Gastroenterology & hepatology · 2024 · 281 citations · Full text

, , +16

1–5 of 74

Authors

593

  1. PJ
    P. J. S. M. Kerstens

    Amsterdam UMC Location Vrije Universiteit Amsterdam, Netherlands

    8 publications · 2.4K citations

    8

    h-index

  2. JK
    Jeska K de Vries‐Bouwstra

    Leiden University Medical Center, Netherlands

    7 publications · 2.3K citations

    7

    h-index

  3. CF
    Cornelia F Allaart

    Leiden University Medical Center, Netherlands

    7 publications · 2.4K citations

    7

    h-index

  4. YP
    Y P M Goekoop-Ruiterman

    Leiden University Medical Center, Netherlands

    7 publications · 2.3K citations

    7

    h-index

  5. HK
    H. K. Ronday

    Leiden University Medical Center, Netherlands

    6 publications · 2.3K citations

    6

    h-index

1–5 of 593

Institutions

282

  1. Leiden University Medical Center

    Leiden, The Netherlands

    12 h-index

    51 publications

    10.2K citations

  2. Amsterdam UMC Location Vrije Universiteit Amsterdam

    Amsterdam, The Netherlands

    10 h-index

    28 publications

    4.8K citations

  3. University of Colorado Denver

    Denver, United States

    10 h-index

    68 publications

    6.5K citations

  4. National Jewish Health

    Denver, United States

    7 h-index

    13 publications

    2.8K citations

  5. University of Aberdeen

    Aberdeen, United Kingdom

    7 h-index

    8 publications

    163 citations

  6. Haga Hospital

    The Hague, Netherlands

    7 h-index

    9 publications

    2.4K citations

  7. University of Groningen

    Groningen, The Netherlands

    6 h-index

    9 publications

    283 citations

  8. Harvard University

    Cambridge, United States

    6 h-index

    8 publications

    346 citations

1–8 of 282

Venues

  1. Annals of the Rheumatic Diseases

    ARD · 8 publications · 859 citations

    8

    h-index

  2. PubMed

    Repository · 6 publications · 518 citations

    6

    h-index

  3. Arthritis & Rheumatism

    4 publications · 2.1K citations

    4

    h-index

  4. 4

    h-index

  5. International Journal of COPD

    3 publications · 91 citations

    3

    h-index

1–5