Inhibition of Cleavage of Large Poliovirus-Specific Precursor Proteins in Infected HeLa Cells by Inhibitors of Proteolytic Enzymes

Abstract

Inhibitors of chymotrypsin interfere with the post-translational cleavage of large poliovirus-specific polypeptides in the molecular weight range of 100,000 to 250,000 in infected HeLa cells.