JAUNDICE DUE TO METHYL TESTOSTERONE THERAPY

Abstract

Case Reports1 January 1954JAUNDICE DUE TO METHYL TESTOSTERONE THERAPYP. J. ALMADEN, M.D., S. W. Ross, M.D.P. J. ALMADEN, M.D.Search for more papers by this author, S. W. Ross, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-1-146 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere is increasing evidence that a distinct type of hepatic damage is produced in some patients by administration of methyl testosterone. We have found reports of 18 such cases in the medical literature.1, 2, 4, 5, 7 References by many authors to unpublished observations of a similar nature suggest that the actual number of cases is much greater. As we become more aware of jaundice as a possible effect of methyl testosterone, we may expect this condition to be recognized more frequently.The patient whose record is summarized here developed severe jaundice of the type first reported by Werner in...Bibliography1. Werner SC: Clinical syndromes associated with gonadal failure in men, Am. J. Med. 3: 52, 1947. CrossrefMedlineGoogle Scholar2. WernerHangerKritzler SCFMR: Jaundice during methyl testosterone therapy, Am. J. Med. 8: 325, 1950. CrossrefMedlineGoogle Scholar3. Kinsell LW: Factors affecting protein balance in the presence of chronic viral liver damage, Gastroenterology 11: 672, 1948. MedlineGoogle Scholar4. BrickKyle IBLH: Jaundice of hepatic origin during the course of methyl testosterone therapy, New England J. Med. 246: 176, 1952. CrossrefMedlineGoogle Scholar5. Wood JC: Jaundice due to methyl testosterone therapy, J. A. M. A. 150: 1484, 1952. CrossrefMedlineGoogle Scholar6. WilkinsFleischmannHoward LWJE: Creatinuria induced by methyl testosterone in treatment of dwarfed boys and girls, Bull. Johns Hopkins Hosp. 69: 493, 1941. Google Scholar7. BonnerHomburger CDF: Jaundice of hepatocellular type during methyl testosterone therapy, Bull. New England M. Center 14: 87, 1952. MedlineGoogle Scholar8. Schiff L: Personal communication. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Little Rock, Arkansas*Received for publication June 12, 1953.From the Department of Medicine, University of Arkansas School of Medicine, Little Rock, Arkansas. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEffects of androgens and related steroids on liver functions and enzymesErfahrungen mit dem Androgen-Präparat MesterolonBibliographyEffect of Methandienone (Methyl Androstenolone, 1-Dehydro-17 α-Methyl Testosterone) (Geabol, Dianabol) on Pituitary FunctionThe Importance of the Measurement of Enzyme Activity in MedicineIntrahepatic Cholestasis vs. Posthepatic Jaundice: Methods of Diagnosis: With a Note on Hypercholesteremic Xanthomatosis in a Patient with Chlorpromazine CholestasisCLINICAL AND LABORATORY MANIFESTATIONS OF HEPATOTOXICITYDie Wirkung von Methandrostenolon auf die menschliche LeberIntrahepatic cholestasis following administration of chlorpropamideDRUG-INDUCED HEPATIC INJURY*HANS POPPER, M.D., F.A.C.P., FENTON SCHAFFNER, M.D., F.A.C.P.HYPERSENSITIVITY REACTION FROM ACETARSOL PESSARIESDrug reactions characterized by cholestasis associated with intrahepatic biliary tract obstructionChlorpromazine jaundiceHepatitis und posthepatitische LeberkrankheitenJaundice Due to Methyltestosterone TherapyDiseases of Medical ProgressTierexperimentelle Untersuchungen �ber die Megaphen-Wirkung auf die LeberINTRAHEPATIC OBSTRUCTIVE JAUNDICE (PRIMARY CHOLESTASIS), A CLINICOPATHOLOGIC SYNDROME OF VARIED ETIOLOGY: A REVIEW WITH OBSERVATIONS OF THE USE OF CORTICOTROPIN AS A DIAGNOSTIC TOOL*HENRY C. JOHNSON JR., M.D., JOHN P. DOENGES, M.D.CHLORPROMAZINE (THORAZINE) HEPATITIS: REPORT OF THREE CASES*HERMAN GOLD, M.D., F.A.C.P., FRANK ROSENBERG, M.D., WILLIAM CAMPBELL, M.D.Chlorpromazine (Thorazine) HepatitisCholangiolitic Hepatitis 1 January 1954Volume 40, Issue 1Page: 146-152KeywordsTestosterone ePublished: 1 December 2008 Issue Published: 1 January 1954 PDF downloadLoading ...