Jaundice of Hepatic Origin during the Course of Methyl-Testosterone Therapy

Abstract

THE occurrence of jaundice during methyl-testosterone therapy was recently reported by Kinsell1 and Werner, Hanger and Kritzler.2 In view of the apparent rarity of this toxic effect of a commonly used drug, as reflected by the sparsity of cases reported in the literature, and of the distinctive features of this type of liver disease, we are reporting two cases of jaundice that occurred during the sublingual use of methyl testosterone. Furthermore, widespread knowledge of this possibility may stimulate others to report and may serve as a warning that methyl-testosterone administration should be considered in the differential diagnosis of jaundice—especially in . . .