p53 Point mutations in dysplastic and cancerous ulcerative colitis lesions

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

Genetic Alterations during Colorectal-Tumor Development

Bert Vogelstein, Eric R. Fearon, Stanley R. Hamilton et al. · New England Journal of Medicine · 1988 · 6.7K citations

Tumor Biology, Somatic Variant, Tumor Heterogeneity +13

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

Masato Orita, Youichi Suzuki, Takao Sekiya et al. · Genomics · 1989 · 3.5K citations

Sensitive Detection, Polymerase Chain Reaction, Genetic Analysis +12

Dysplasia in inflammatory bowel disease: Standardized classification with provisional clinical applications

Robert H. Riddell, Harvey Goldman, David F. Ransohoff et al. · Human Pathology · 1983 · 1.9K citations

Functional Gastrointestinal Disorder, Standardized Classification, Gastroenterology +5

Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53

Suzanne J. Baker, Sanford D. Markowitz, Eric R. Fearon et al. · Science · 1990 · 1.8K citations

Wild-type P53, Oncology, Oncogenic Agent +13