Distribution, excretion and metabolism of neuroleptics of the butyrophenone type

IS IT POSSIBLE TO PREDICT THE CLINICAL EFFECTS OF NEUROLEPTIC DRUGS (MAJOR TRANQUILLIZERS) FROM ANIMAL DATA?I. "NEUROLEPTIC ACTIVITY SPECTRA" FOR RATS.

Patricia A. Janssen, Niemegeers Cj, Schellekens Kh · PubMed · 1965 · 348 citations

Medicine, Pharmacokinetics, Pharmacology +12

Chemistry and Pharmacology of CNS Depressants Related to 4-(4-Hydroxy-4-phenylpiperidino)butyrophenone Part I--Synthesis and screening data in mice

Paul A. J. Janssen, Anton H. M. Jageneau, Paul J. A. Demoen et al. · Journal of Medicinal Chemistry · 1959 · 154 citations

Medicine, Medicinal Chemistry, Pharmacology +8

4-Substituted Piperidines. II. Reaction of 1-Benzyl-4-cyano-4-t-aminopiperidines with Organometallic Compounds

Bert Hermans, Paul Van Daele, Cornelis van de Westeringh et al. · Journal of Medicinal Chemistry · 1965 · 13 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9