IS IT POSSIBLE TO PREDICT THE CLINICAL EFFECTS OF NEUROLEPTIC DRUGS (MAJOR TRANQUILLIZERS) FROM ANIMAL DATA?I. "NEUROLEPTIC ACTIVITY SPECTRA" FOR RATS.

Patricia A. Janssen, Niemegeers Cj, Schellekens Kh

PubMed

Neuroleptic Activity SpectraPsychoactive DrugPharmacological StudyMedicineFrom Animal Data +8

Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine.

Patricia A. Janssen, Niemegeers Cj, Schellekens Kh, +6

PubMed

Molecular PharmacologyMedicinal ChemistryPsychoactive DrugComparative PharmacologyMedicine +8

Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data?

Patricia A. Janssen, Niemegeers Cj, Schellekens Kh

PubMed

Psychoactive DrugPharmacological StudyNeurophysiologyNeuroanatomyMedicine +12

Sufentanil, a very potent and extremely safe intravenous morphine-like compound in mice, rats and dogs.

Niemegeers Cj, Schellekens Kh, Van Bever Wf, +1

Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)

PharmacotherapyExperimental PharmacologyMedicinal ChemistryPharmacological StudyR 30 +15

The pharmacology of dehydrobenzperidol, a new potent and short acting neuroleptic agent chemically related to Haloperidol.

Patricia A. Janssen, Niemegeers Cj, Schellekens Kh, +2

PubMed

Molecular PharmacologyMedicinal ChemistryPsychoactive DrugNeuroleptic AgentMedicine +10

Domperidone, a novel and safe gastrokinetic anti-nauseant for the treatment of dyspepsia and vomiting.

Reyntjens Aj, Niemegeers Cj, Van Nueten Jm, +7

PubMed

Drug SafetyMedicinal ChemistryAdrenolytic Adverse EffectsAvailable Anti-emeticsPsychotropic Medication +11

The pharmacology of fluspirilene (R 6218), a potent, long-acting and injectable neuroleptic drug.

Patricia A. Janssen, Niemegeers Cj, Schellekens Kh, +6

PubMed

Pharmaceutical ScienceMedicineR 6218Pharmacological AgentNeuropharmacology +7

Chemistry and pharmacology of compounds related to 4-(4-hydroxy-4-phenyl-piperidino)-butyrophenone. III. Duration of antiemetic action and oral effectiveness of Haloperidol (R 1625) and of chlorpromazine in dogs.

Patricia A. Janssen, Niemegeers Cj, Schellekens Kh

PubMed

Molecular PharmacologyMedicinal ChemistryPharmacological StudyMedicineAntiemetic Action +9

Bezitramide (R 4845), a new potent and orally long-acting analgesic compound.

Patricia A. Janssen, Niemegeers Cj, Schellekens Kh, +8

PubMed

Molecular PharmacologyMedicinal ChemistryHealth SciencesPain MedicinePharmacology +10