Publication | Open Access
Tightening LP Relaxations for MAP using Message Passing
250
Citations
16
References
2012
Year
Mathematical ProgrammingCluster ComputingLarge-scale Global OptimizationEngineeringMachine LearningStandard Lp RelaxationUnsupervised Machine LearningData ScienceRandom MappingBiological Network VisualizationCombinatorial OptimizationDual LpApproximation TheoryInformation TheoryProtein ModelingComputer ScienceLp RelaxationsAlgorithmic Information TheoryBioinformaticsProtein BioinformaticsComputational BiologyLinear ProgrammingSystems Biology
Linear Programming (LP) relaxations have become powerful tools for finding the most probable (MAP) configuration in graphical models. These relaxations can be solved efficiently using message-passing algorithms such as belief propagation and, when the relaxation is tight, provably find the MAP configuration. The standard LP relaxation is not tight enough in many real-world problems, however, and this has lead to the use of higher order cluster-based LP relaxations. The computational cost increases exponentially with the size of the clusters and limits the number and type of clusters we can use. We propose to solve the cluster selection problem monotonically in the dual LP, iteratively selecting clusters with guaranteed improvement, and quickly re-solving with the added clusters by reusing the existing solution. Our dual message-passing algorithm finds the MAP configuration in protein sidechain placement, protein design, and stereo problems, in cases where the standard LP relaxation fails.
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