Chapter 6 DNA Damage Response and Apoptosis

DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

Emmy P. Rogakou, Duane R. Pilch, Ann H. Orr et al. · Journal of Biological Chemistry · 1998 · 5.3K citations · Full text

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Xuesong Liu, Caryn Naekyung Kim, Jie Yang et al. · Cell · 1996 · 5.2K citations · Full text

Apoptotic Program, Biochemistry, Medicine +11

The expanding role of mitochondria in apoptosis.

X. Wang · PubMed · 2001 · 2.4K citations

Apoptosis, Cell Death, Mitochondrial Biology +19

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

Tanya T. Paull, Emmy P. Rogakou, Vikky Yamazaki et al. · Current Biology · 2000 · 2.1K citations · Full text

Histone Modifications, Dna Damage, Epigenetic Change +16

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

Kurt Degenhardt, Robin Mathew, Brian Beaudoin et al. · Cancer Cell · 2006 · 2K citations · Full text

Inflammation, Cell Autophagy, Tumor Cell Survival +11