The Journal of Immunology · 1968 · 32 citations · 0 references
Life SciencesImmunologyPathologyHypersensitivityImmunizationVaccinologyAdjuvant DevelopmentHumoral ImmunityMammalian ImmunologyTesticular ImmunologyVaccinationAdjuvant Mechanism Of ActionAdjuvant MechanismsAdjuvant-induced ImmunityAnimal ImmunizationAntigen-adjuvant InteractionsImmunological AdjuvantsVaccination AdjuvantsVaccine Adjuvant Therapy
Summary B. pertussis phase I vaccine is an effective adjuvant in the production of experimental aspermatogenesis in that profound testicular damage is produced in most of the animals. Pertussis organisms thereby are found to enhance hypersensitivity of the delayed as well as of the immediate type. The mechanism of action of pertussis vaccine is probably different from that of oily adjuvants.