Concepedia

Biochemical and functional characterization of a recombinant monomeric factor VIII–Fc fusion protein

Robert Peters, Garabet G. Toby, Qi Lü, T. Liu, John D. Kulman, S C Low, Alan J. Bitonti, Glenn F. Pierce

Journal of Thrombosis and Haemostasis · 2012 · 123 citations · 12 references

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Concepts

References

12

Structure of human factor VIII

Gordon A. Vehar, Bruce A. Keyt, Dan Eaton et al. · Nature · 1984 · 895 citations

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A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity.

J J Toole, Debra D. Pittman, Elizabeth C. Orr et al. · Proceedings of the National Academy of Sciences · 1986 · 314 citations · Full text

, , +15

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients

Jerry S. Powell, Neil C. Josephson, Doris Quon et al. · Blood · 2012 · 234 citations · Full text

, , +12

Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway

Alan J. Bitonti, Jennifer Dumont, Susan C. Low et al. · Proceedings of the National Academy of Sciences · 2004 · 229 citations · Full text

, , +13

Prolonged activity of factor IX as a monomeric Fc fusion protein

Robert Peters, Susan C. Low, George D. Kamphaus et al. · Blood · 2010 · 193 citations

, , +11