Concepedia

Blocking TGF-β–Smad2/3 innate immune signaling mitigates Alzheimer-like pathology

Terrence Town, Yasmina Laouar, Christopher Pittenger, Takashi Mori, Christine A. Szekely, Jun Tan, Ronald S. Duman, Richard A. Flavell

Nature Medicine · 2008 · 420 citations · 27 references

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27

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

, , +17

Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties

Frédéric Geissmann, Steffen Jung, Dan R. Littman · Immunity · 2003 · 3.3K citations · Full text

, , +15

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

Bahareh Ajami, Jami Bennett, Charles Krieger et al. · Nature Neuroscience · 2007 · 1.6K citations

, , +14

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

Leigh A. Holcomb, Marcia N. Gordon, Eileen McGowan et al. · Nature Medicine · 1998 · 1.4K citations

, , +17

Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report

James A. R. Nicoll, David G. Wilkinson, Clive Holmes et al. · Nature Medicine · 2003 · 1.4K citations

, , +16