Prognostic and diagnostic implications of epithelial cell adhesion/activating molecule ( <scp>EpCAM</scp> ) expression in renal tumours: a retrospective clinicopathological study of 948 cases using tissue microarrays

Abstract

The histological subtypes associated with a high rate of EpCAM expression were cpRCC and pRCC. This retrospective analysis demonstrated a trend towards longer OS and PFS for all major RCC subtypes. EpCAM expression had significant prognostic value in patients with cpRCC and pRCC. Furthermore, EpCAM overexpression in high grade RCC may be a helpful marker for prognostication.