Chemical and Pharmaceutical Bulletin · 1982 · 35 citations · 1 references
Life SciencesMedicinal ChemistryPlant SciencesDrug DiscoveryEthnobotanyPlant BiochemistryAlkaloid BiosynthesisAromatic PlantsMedicinal Plant KnowledgeMedicinal PlantsPlant Natural Product BiosynthesisAlkaloid GlycosidesBioactive ConstituentsIndole AlkaloidsIndole DerivativesLactam SynthesisPlant Alkaloids
A new glycoindole alkaloid, rhynchophine, was isolated from the leaves of Uncaria rhynchophylla MIQ. and its structure was elucidated as 6'-feruloyl vincoside lactam (IV). A partial synthesis was achieved by the use of vincoside lactam as the starting material. Five known compounds were also newly isolated from the same plant, namely, vallesiachotamine, vincoside lactam, strictosamide, hyperin and trifolin.
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