Concepedia

Partial correction of endogenous ΔF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing

Xiaoming Liu, Qinshi Jiang, S. Gary Mansfield, M. Puttaraju, Yulong Zhang, Weihong Zhou, Jonathan Cohn, Mariano A. García-Blanco, Lloyd G. Mitchell, John F. Engelhardt

Nature Biotechnology · 2002 · 169 citations · 22 references

DOI

Concepts

References

22

Submucosal glands are the predominant site of CFTR expression in the human bronchus

John F. Engelhardt, James R. Yankaskas, Stephen A. Ernst et al. · Nature Genetics · 1992 · 649 citations

, , +13

Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

Larry G. Johnson, John C. Olsen, Balázs Sarkadi et al. · Nature Genetics · 1992 · 435 citations

, , +16

Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1–deleted adenoviruses

John F. Engelhardt, Yiping Yang, Leslie D. Stratford-Perricaudet et al. · Nature Genetics · 1993 · 296 citations

, , +14

A simple method for the rapid generation of recombinant adenovirus vectors

R.D. Anderson, RE Haskell, Haibin Xia et al. · Gene Therapy · 2000 · 261 citations

, , +11

Expression of the cystic fibrosis gene in adult human lung.

John F. Engelhardt, Monica L. Zepeda, Jonathan Cohn et al. · Journal of Clinical Investigation · 1994 · 256 citations · Full text

, , +12