M. Puttaraju

Spliceosome-mediated RNA trans-splicing as a tool for gene therapy

M. Puttaraju, Sharon F. Jamison, S. Gary Mansfield et al. · Nature Biotechnology · 1999 · 190 citations

Gene Therapies, In Vivo Gene Therapy, Natural Sciences +8

Group I permuted intron-exon (PIE) sequences self-splice to produce circular exons

M. Puttaraju, Michael D. Been · Nucleic Acids Research · 1992 · 180 citations · Full text

Partial correction of endogenous ΔF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing

Xiaoming Liu, Qinshi Jiang, S. Gary Mansfield et al. · Nature Biotechnology · 2002 · 169 citations

Transcriptional Regulation, Fibrosis, Molecular Physiology +12

Repair of CFTR mRNA by spliceosome-mediated RNA trans-splicing

S. Gary Mansfield, Jolanta Kole, M. Puttaraju et al. · Gene Therapy · 2000 · 97 citations

Rna Splicing, Rna Biology, Cftr Mrna +6

Messenger RNA Repair and Restoration of Protein Function by Spliceosome-Mediated RNA Trans-Splicing

M. Puttaraju, Janet DiPasquale, Carl C. Baker et al. · Molecular Therapy · 2001 · 77 citations · Full text

Functional Repertoire, Genome Instability, Protein Function +15