Dynamic activation of endothelial nitric oxide synthase by Hsp90

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Life Sciences, Cell Biology, Physiology +15

Characterization of three inhibitors of endothelial nitric oxide synthase <i>in vitro</i> and <i>in vivo</i>

Daryl D. Rees, Richard Palmer, Richard Schulz et al. · British Journal of Pharmacology · 1990 · 1.9K citations · Full text

Medicine, Cardiology, Pharmacology +12

Crystal Structure of an Hsp90–Geldanamycin Complex: Targeting of a Protein Chaperone by an Antitumor Agent

C. Erec Stebbins, Alicia A. Russo, Christine Schneider et al. · Cell · 1997 · 1.4K citations · Full text

Life Sciences, Biochemistry, Oncology +17

Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone

Chrisostomos Prodromou, S. Mark Roe, Ronan O’Brien et al. · Cell · 1997 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Flow Effects on Prostacyclin Production by Cultured Human Endothelial Cells

John A. Frangos, Suzanne G. Eskin, Larry V. McIntire et al. · Science · 1985 · 1.2K citations

Life Sciences, Pharmacology, Physiology +12