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The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line1 1Abbreviations: AP = apical; BL = basolateral; 2-DOG = 2-deoxyglucose; HBSS = Hanks balanced salt solution; FITC = fluorescein isothiocyanate; HEPES = N-2-hydroxyethyl piperazine-N-4-butanesulfonic acid; HMW = high molecular weight; LMW = low molecular weight; MES = morpholinoethane sulfonic acid; PBS+ = phosphate buffered saline; PEI = polyethylenimine; TEER = trans-epithelial electrical resistance; TRITC = tetramethylrodamine isothiocyanate.