Activating Endogenous Neural Precursor Cells Using Metformin Leads to Neural Repair and Functional Recovery in a Model of Childhood Brain Injury

Metformin improves healthspan and lifespan in mice

Alejandro Martín‐Montalvo, Evi M. Mercken, Sarah J. Mitchell et al. · Nature Communications · 2013 · 1.4K citations · Full text

Lifespan Extension, Longevity, Medicine +4

Brain plasticity and behaviour in the developing brain.

Bryan Kolb, Robbin Gibb · PubMed · 2011 · 479 citations

Metformin and Insulin Suppress Hepatic Gluconeogenesis through Phosphorylation of CREB Binding Protein

Ling He, Amin Sabet, Stephen Djedjos et al. · Cell · 2009 · 478 citations · Full text

Metabolic Syndrome, Insulin Signaling, Signal Transduction +13

Metformin Activates an Atypical PKC-CBP Pathway to Promote Neurogenesis and Enhance Spatial Memory Formation

Jing Wang, Denis Gallagher, Loren M. DeVito et al. · Cell stem cell · 2012 · 466 citations · Full text

Synaptic Plasticity, Developmental Biology, Synaptic Signaling +9

Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations

Cindi M. Morshead, Patricia Benveniste, Norman N. Iscove et al. · Nature Medicine · 2002 · 388 citations

Epigenetic Alterations, Medicine, Genetics +13