Multiple and cooperative phosphorylation events regulate the CREM activator function.

[6] Use of T7 RNA polymerase to direct expression of cloned genes

F. William Studier, Alan H. Rosenberg, John J. Dunn et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 1990 · 6.6K citations · Full text

Engineering, Rna Biology, Molecular Biology +10

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

Gustavo González, Marc Montminy · Cell · 1989 · 2.5K citations

Somatostatin Gene Transcription, Molecular Regulation, Cellular Physiology +17

CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

Morgan Sheng, Margaret A. Thompson, Michael E. Greenberg · Science · 1991 · 1.5K citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

William J. Boyle, Peter van der Geer, Tony Hunter · Methods in enzymology on CD-ROM/Methods in enzymology · 1991 · 1.5K citations

Biochemistry, Separation Science, Phosphoamino Acid Analysis +8

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

Karen Yamamoto, G. González, William Biggs et al. · Nature · 1988 · 1.3K citations

Transcriptional Regulation, Signal Transduction, Nuclear Factor Creb +5