OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Young‐Yun Kong, Hiroki Yoshida, Ildiko Sarosi, +14

Nature

Developmental BiologyKey RegulatorBone Morphogenic ProteinCell SignalingLymphocyte Development +9

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

Young‐Yun Kong, Ulrich Feige, Iidiko Sarosi, +17

Nature

InflammationRheumatologyRheumatoid DisorderSclerostinAdjuvant Arthritis +12

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

Hailing Hsu, David L. Lacey, Colin R. Dunstan, +18

Proceedings of the National Academy of Sciences

InflammationOsteoprotegerin LigandSclerostinSignal TransductionOpg Transgenic Mice +12

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

William J. Boyle, Peter van der Geer, Tony Hunter

Methods in enzymology on CD-ROM/Methods in enzymology

BiochemistrySeparation SciencePhosphoamino Acid AnalysisBioanalysisAnalytical Chemistry +6

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

Robert Chiu, William J. Boyle, Jennifer Meek, +3

Cell

Transcriptional RegulationSystems BiologySignal TransductionSignaling PathwayCell Regulation +10

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

Ji Li, Ildiko Sarosi, Xiaoqiang Yan, +20

Proceedings of the National Academy of Sciences

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

William J. Boyle, Tod Smeal, Libert H.K. Defize, +4

Cell

ChromatinSignal TransductionProtein Kinase CCell RegulationNatural Sciences +9

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

Peter Angel, Elizabeth A. Allegretto, S.T. Okino, +4

Nature

Transcriptional RegulationNatural SciencesGeneticsGenomic MechanismGene Regulation +6

The Osteoclast Differentiation Factor Osteoprotegerin-Ligand Is Essential for Mammary Gland Development

Jimmie E. Fata, Young‐Yun Kong, Ji Li, +10

Cell

SclerostinDevelopmental BiologyBone Morphogenic ProteinMammary GlandBreast Cancer +9

The Ligand for Osteoprotegerin (OPGL) Directly Activates Mature Osteoclasts

Teresa L. Burgess, Yixin Qian, Stephen A. Kaufman, +9

The Journal of Cell Biology

Mature OcsOrthopaedic SurgeryOsteoporosisCellular PhysiologyBone Biology +15