Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras

SH2 domains recognize specific phosphopeptide sequences

Cell · 1993 · 2.7K citations

Protein Function, Signal Transduction, Medicine +7

A family of cytokine-inducible inhibitors of signalling

Robyn Starr, Tracy A. Willson, Elizabeth M. Viney et al. · Nature · 1997 · 2.1K citations · Full text

Inflammation, Cytokine, Signal Transduction +6

A new protein containing an SH2 domain that inhibits JAK kinases

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Protein Function, Signal Transduction, Signaling Pathway +12

Structure and function of a new STAT-induced STAT inhibitor

Tetsuji Naka, Masashi Narazaki, Moritoshi Hirata et al. · Nature · 1997 · 1.3K citations · Full text

Biochemistry, Medicine, Mechanism Of Action +5

A Cytoplasmic Protein Stimulates Normal N- <i>ras</i> p21 GTPase, But Does Not Affect Oncogenic Mutants

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