Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry

Nucleic Acid ChemistryEngineeringNatural SciencesRna IsolationBiotechnology +5

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi

Analytical Biochemistry

EngineeringNatural SciencesRna IsolationRna Structure PredictionNucleic Acid Biochemistry +5

Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity☆, ☆☆

Christi A Matteoni, Zobair M. Younossi, T GRAMLICH, +3

Gastroenterology

ObesityMetabolic SyndromeMetabolic Associated SteatohepatitisHepatic DisordersHepatology +10

IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

Gökhan S. Hotamışlıgil, Pascal Peraldi, Adriane I. Budavari, +3

Science

Protection from obesity-induced insulin resistance in mice lacking TNF-α function

K. Teoman Uysal, Sarah M. Wiesbrock, Michael W. Marino, +1

Nature

ObesityMetabolic SyndromeInflammationInsulin ResistanceInsulin Signaling +12

Association of nonalcoholic fatty liver disease with insulin resistance

Giulio Marchesini, Mara Brizi, Antonio Maria Morselli‐Labate, +5

The American Journal of Medicine

Insulin ResistanceObesityMetabolic SyndromeMetabolic Associated SteatohepatitisHepatology +10

Metabolic Effects of Metformin in Non-Insulin-Dependent Diabetes Mellitus

Michael Stümvoll, N. Nurjhan, G. Perriello, +2

New England Journal of Medicine

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy

Iichiro Shimomura, Robert E. Hammer, Shinji Ikemoto, +2

Nature

ObesityMetabolic SyndromeInsulin ResistanceCongenital LipodystrophyDevelopmental Biology +7

Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis

Shi Qi Yang, Hui Lin, M. Daniel Lane, +2

Proceedings of the National Academy of Sciences

ImmunologyCell DeathPathologyFatty Liver DiseaseInflammation +20

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

Iichiro Shimomura, Robert E. Hammer, James A. Richardson, +4

Genes & Development