2006 · 45 citations · 43 references
Life SciencesBiologyMicrobiologyBacteriologyMicrobial EcologyMicrobial PhysiologyBacterial EcologyBacterial PhysiologyBacterial SurvivalMicrobial Cell-cell CommunicationMicrobial ControlQuorum SensingConcentrationPopulation Density DependencePopulation Density SensingQuorum Sensing Gene RegulationQuorum Sensing Signal SynthesisQuorum Sensing Signaling
Bacterial cells exhibit several density-dependent pheno-types. Such a biological phenomenon is referred to as quorum-sensing. Quorum-sensing is achieved through the production of an autoinducer by the organism, which upon acquiring a threshold concentration, a drect reflection of population density, is able to activate the genes, bringing into effect the concerned phenotypes. While this cell-to-cell communication has played an important role in many diverse community-based functions, it also helps the establi hment of a population in changing environment according to the requirement. This sensing can be put to numerous uses such as in controlling plant and animal diseases, regulation of the production of useful/toxic fermentation products, etc. in the future.
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Structural identification of autoinducer of Photobacterium fischeri luciferase
Anatol Eberhard, A. L. Burlingame, Carolyn Eberhard et al. · Biochemistry · 1981 · 978 citations
Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa
Everett C. Pesci, James P. Pearson, Patrick C. Seed et al. · Journal of Bacteriology · 1997 · 906 citations · Full text