Concepedia

SALL4 is a key transcription regulator in normal human hematopoiesis

Chong Gao, Nikki R. Kong, Ailing Li, Hiro Tatetu, Shikiko Ueno, Youyang Yang, Jie He, Jianchang Yang, Yupo Ma, Grace S. Kao,

Transfusion · 2012 · 59 citations · 29 references

DOI

Abstract

Taken together, SALL4 is a key regulator in normal human hematopoiesis and the mechanism of its function is at least in part through the HOXA9. Future study will determine whether modulating the SALL4/HOXA9 pathway can be used in cellular therapy such as cord blood expansion and/or myeloid engraftment.

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