The Renaissance of Natural Products as Drug Candidates

A Planning Strategy for Diversity‐Oriented Synthesis

Martin D. Burke, Stuart L. Schreiber · Angewandte Chemie International Edition · 2003 · 1.5K citations

Pharmacy, Chemistry, Medicinal Chemistry +11

Total synthesis of halichondrin B and norhalichondrin B

Thomas D. Aicher, Keith R. Buszek, Francis G. Fang et al. · Journal of the American Chemical Society · 1992 · 390 citations

Natural Sciences, Chemistry, Analytical Chemistry +5

A Convergent Enantioselective Route to Structurally Diverse 6-Deoxytetracycline Antibiotics

Mark G. Charest, C. Lerner, Jason D. Brubaker et al. · Science · 2005 · 297 citations

Pharmacy, Medicinal Chemistry, Drug Design +8

Evolution of a Gram-Scale Synthesis of (+)-Discodermolide

Amos B. Smith, Thomas J. Beauchamp, Matthew J. LaMarche et al. · Journal of the American Chemical Society · 2000 · 236 citations

Pharmacy, Chemistry, Medicinal Chemistry +15

Discovery of Potent Cell Migration Inhibitors through Total Synthesis:  Lessons from Structure−Activity Studies of (+)-Migrastatin

Jón T. Njardarson, Christoph Gaul, Dandan Shan et al. · Journal of the American Chemical Society · 2004 · 165 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13