HYPERPARATHYROIDISM ASSOCIATED WITH PAGET'S DISEASE

Abstract

Case Reports1 May 1961HYPERPARATHYROIDISM ASSOCIATED WITH PAGET'S DISEASENORMAN N. KOHN, M.D., RALPH M. MYERSON, M.D., F.A.C.P.NORMAN N. KOHN, M.D.Search for more papers by this author, RALPH M. MYERSON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-5-985 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe clinical, biochemical, radiologic, and histopathologic findings of hyperparathyroidism are sufficiently characteristic in the majority of instances to allow the diagnosis to be made with a fair degree of certainty prior to surgical exploration. Occasionally, however, difficulty is encountered. Atypical features may be present which render the preoperative diagnosis uncertain. When another disorder coexists, which, in itself may present features similar to those seen in hyperparathyroidism, making the diagnosis is apt to be especially difficult.In the present case the patient was found to have typical radiologic evidence of Paget's disease, confirmed by bone biopsy. Certain features, however, were atypical...Bibliography1. SchaafKyle MLH: Measurement of per cent renal phosphorus reabsorption in the diagnosis of hyperparathyroidism. Amer. J. Med. Sci. 228: 262-268, 1954. CrossrefMedlineGoogle Scholar2. KyleSchaafCanary LHMJJ: Phosphate clearance in the diagnosis of parathyroid dysfunction. Amer. J. Med. 24: 240-248, 1958. CrossrefMedlineGoogle Scholar3. Dent CE: Cortisone test for hyperparathyroidism. Brit. Med. J. 1: 230, 1956. CrossrefGoogle Scholar4a. AlbrightReifenstein FEC: The parathyroid glands and metabolic bone disease. The Williams & Wilkins Co., Baltimore, 1948, p. 289. Google Scholar4b. Ibid., p. 113. Google Scholar5. Zimmerman SP: Hyperparathyroidism simulating Paget's disease. Ann. Intern Med. 30: 675-681, 1949. LinkGoogle Scholar6. Rosen H: Paget's disease complicated by hyperparathyroidism. Bull. Hosp. Joint Dis. 11: 113-127, 1950. MedlineGoogle Scholar7. RockneyKleemanMaxwell RECRMH: Hyperparathyroidism in a patient with Paget's disease and carcinoma of the breast. Arch. Intern. Med. 104: 797-801, 1959. CrossrefMedlineGoogle Scholar8. Page F: Diagnostic problems: No. 14. A case of malignant melanoma, steatorrhea, Paget's disease and hyperparathyroidism. Arch. Middlesex Hospital 4: 215-218, 1954. MedlineGoogle Scholar9. GutmanParsons ABWB: Hyperparathyroidism simulating or associated with Paget's disease, with three illustrative cases. Ann. Intern. Med. 12: 13-25, 1938. LinkGoogle Scholar10. Law WB: Hyperparathyroidism simulating Paget's disease. Med. J. Aust. 2: 455-457, 1957. CrossrefGoogle Scholar11a. Snapper I: Bone disease in medical practice. Grune & Stratton, New York, 1952, p. 68. Google Scholar11b. Ibid., p. 72. Google Scholar12. Snapper I: Rare manifestations of metabolic bone disease. Charles C Thomas, Springfield, Ill., 1952, p. 82. Google Scholar13. Black BM: Hyperparathyroidism. Charles C Thomas, Springfield, Ill., 1953, p. 62. Google Scholar14. Ballin M: Parathyroidism in reference to orthopaedic surgery. J. Bone Joint Surg. 15: 120-134, 1933. Google Scholar15. ColtLyall GHA: Case of osteitis deformans treated with parathormone. Brit. Med. J. 2: 10-11, 1933. CrossrefMedlineGoogle Scholar16. Schmorl G: Uber ostitis deformans Paget. Virchow. Arch. Path. Anat. 283: 694-751, 1932. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication August 24, 1960.From the Medical Service of the Veterans Administration Hospital, Philadelphia, Pa.†Resident in Medicine.‡Assistant Chief, Medical Service, Veterans Administration Hospital, and Clinical Professor of Medicine, Woman's Medical College of Pennsylvania, Philadelphia, Pa.Requests for reprints should be addressed to Ralph M. Myerson, M.D., Assistant Chief, Medical Service, Veterans Administration Hospital, 39th St. and Woodland Ave., Philadelphia 4, Pa. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCoexistence of Primary Hyperparathyroidism and Paget DiseaseWhat Is the Relationship Between Paget's Disease of Bone and Hyperparathyroidism?Primary hyperparathyroidismABNORMAL VITAMIN D METABOLISM IN PAGET'S DISEASE OF BONEHypercalcaemia due to immobilization of a patient with Paget’s disease of bone.Case report 94HYPERCALCAEMIA IN PAGET'S DISEASE OF BONEPLASMAPHERESIS IN THE TREATMENT OF DIALYSIS ENCEPHALOPATHYHYPERCALCÆMIA DUE TO IMMOBILISATION IN PAGET'S DISEASE OF BONEVITAMIN-D ANALOGUES AND RENAL FUNCTIONPseudohyperparathyroidism due to malignant tumorsHYPERCALCEMIA—DOUBLED CAUSES AND A DILEMMAE. J. H. 1 May 1961Volume 54, Issue 5Page: 985-992KeywordsBiopsyBoneHospital medicineHyperparathyroidismMedical servicesResidency ePublished: 1 December 2008 Issue Published: 1 May 1961 PDF downloadLoading ...