HYPERPARATHYROIDISM SIMULATING OR ASSOCIATED WITH PAGET'S DISEASE; WITH THREE ILLUSTRATIVE CASES

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Article1 July 1938HYPERPARATHYROIDISM SIMULATING OR ASSOCIATED WITH PAGET'S DISEASE; WITH THREE ILLUSTRATIVE CASESALEXANDER B. GUTMAN, W. BARCLAY PARSONSALEXANDER B. GUTMANSearch for more papers by this author, W. BARCLAY PARSONSSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-1-13 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptGeneralized osteitis fibrosa cystica (von Recklinghausen's disease) and osteitis deformans (Paget's disease) were regarded formerly as related variants of a single skeletal disease. This concept, however, proved irreconcilable with subsequent clinical, roentgenologic, biochemical and pathologic observations and the consensus now is that generalized osteitis fibrosa cystica and osteitis deformans are discrete and unrelated entities.1 Generalized osteitis fibrosa cystica has been shown to be due to hyperparathyroidism2 whereas osteitis deformans is not due to hyperparathyroidism but to unknown, probably local, factors influencing bone metabolism.A serious difficulty with the prevailing view, however, lies in the increasing number of patients described as...Bibliography1. MICHAËLIS L a. : Ostitis deformans (Paget) und Ostitis fibrosa (von Recklinghausen), Ergebn. d. Chir. u. Orthopädie, 1933, xxvi, 381. b. HUNTER, D., and TURNBULL, H. M.: Hyperparathyroidism: Generalized osteitis fibrosa, Brit. Jr. Surg., 1931, xix, 203. c. BAUER, W.: Hyperparathyroidism: A distinct disease entity, Jr. Bone and Joint Surg., 1933, xv, 135. d. ALBRIGHT, F., AUB, J. C., and BAUER, W.: Hyperparathyroidism, Jr. Am. Med. Assoc., 1934, cii, 1276. e. GUTMAN, A. B., SWENSON, P. C., and PARSONS, W. B.: The differential diagnosis of hyperparathyroidism, Jr. Am. Med. Assoc., 1934, ciii, 87. Google Scholar2. MANDL F: Klinisches und Experimentelles zur Frage der lokalisierten und generalisierten Ostitis fibrosa, Arch. f. klin. Chir., 1926, cxliii, 1, 245. Google Scholar3. CHRISTELLER E: Referat über die Osteodystrophia fibrosa, Verhandl. d. deutsch. path. Gesellsch., 1926, xxi, 7. Google Scholar4. WILLICH T: Spontane Ausheilungsvorgänge bei generalisierter Osteodystrophia fibrosa, Beitr. z. klin. Chir., 1929, cxlvi, 103. Google Scholar5. MEYER-BORSTEL H: Über die Stellung der Recklinghausenschen zur Pagetschen Knochenerkrankung, Fortschr. a. d. Geb. d. Roentgenstrahlen, 1930, xlii, 493. Google Scholar6. GUTMAN AB: The parathyroid glands, Nelson Loose-Leaf Medicine, 1935 revision, Thomas Nelson & Sons, New York. Google Scholar7. GUTMANKASABACH ABH: Paget's disease (osteitis deformans). Analysis of 116 cases, Am. Jr. Med. Sci., 1936, cxci, 361. CrossrefGoogle Scholar8. GUTMANTYSONGUTMAN ABTLEB: Serum calcium, inorganic phosphorus and phosphatase activity in hyperparathyroidism, Paget's disease, multiple myeloma and neoplastic disease of the bones, Arch. Int. Med., 1936, lvii, 379. CrossrefGoogle Scholar9. GUTMANGUTMANKASABACH ABEBHH: Serum phosphatase activity in seventeen cases of osteoporosis circumscripta of the skull, Proc. Soc. Exper. Biol. and Med., 1935, xxxiii, 295. CrossrefGoogle Scholar10. LINDÉN O: Case of osteitis fibrosa generalisata with well-marked tendency to spontaneous cure, Acta radiol., 1934, xv, 202. CrossrefGoogle Scholar11. KIENBÖCKMARKOVITS RE: Ein Fall von Ostitis fibrosa cystica generalisata, Fortschr. a. d. Geb. d. Roentgenstrahlen, 1930, xli, 904. Google Scholar12. ASK-UPMARK E: Further observations on osteitis fibrosa generalisata, Acta chir. Scandinav., 1931, lxviii, 551. Google Scholar13. KIENBÖCK R: Über die Pagetsche Knochenkrankheit und Epithelkörperchentumoren, Beitr. z. klin. Chir., 1934, clix, 597. Google Scholar14. LIÈVRE JA: L'ostéose parathyroïdienne et les ostéopathies chroniques, Masson et Cie, Paris, 1932. Google Scholar15. MANDL F: Der Kalkstoffwechsel und seine Beziehungen zur Chirurgie der Epithelkörperchen, Beitr. z. klin. Chir., 1935, clxii, 643. Google Scholar16. SCHMORL G: Über Ostitis deformans Paget, Virchow's Arch. f. path. Anat., 1932, cclxxxiii, 694. CrossrefGoogle Scholar17. KASABACHGUTMAN HHAB: Osteoporosis circumscripta of the skull and Paget's disease. Fifteen new cases and a review of the literature, Am. Jr. Roentgenol., 1937, xxxvii, 577. Google Scholar18. SCHMORL G: Demonstrationen, Verhandl. d. deutsch. path. Gesellsch., 1913, xvi, 352. Google Scholar19. PENECKE R: Ueber zwei Fälle von Ostitis fibrosa Recklinghausen mit Epithelkörperchentumoren, Verhandl. d. deutsch. path. Gesellsch., 1926, xxi, 97. Google Scholar20. THOMASONSMITH GL: Hyperparathyroidism, West. Jr. Surg., 1933, xli, 78. Google Scholar21. RIVENMASON SSMF: Adenoma of the parathyroid gland, with hyperparathyroidism, ANN. INT. MED., 1936, ix, 1578. Google Scholar22. HANKE H: Pathologische und theoretische Untersuchungen über Osteodystrophia fibrosa (von Recklinghausen) und ihre Beziehung zu Epithelkörperchentumor, Arch. f. klin. Chir., 1932, clxxii, 366. Google Scholar23. PINELLI L: Descrizione d'un caso presentante processi di osteodistrofia deformante del cranio e della colonna vertebrale e contemporane alter alterazioni di osteite fibrosa cistica degli arti, Annali di radio. e fisica med., 1934, viii, 270. Google Scholar24. LAHEYHAGGART FHGE: Hyperparathyroidism, Surg., Gynec. and Obst., 1935, lx, 1033. Google Scholar25. HOFFHEINZ : Ueber Vergrösserungen der Epithelkörperchen bei Ostitis fibrosa und verwandten Krankheitsbildern, Virchow's Arch. f. path. Anat., 1925, cclvi, 705. CrossrefGoogle Scholar26. SAINTONMILLOT PJL: Les lésions osseuses et parathyroidiennes dans la maladie de Recklinghausen, Ann. d'anat. Path., 1931, viii, 70. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication July 20, 1937. From the Departments of Medicine and Surgery, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCoexistence of Primary Hyperparathyroidism and Paget DiseaseWhat Is the Relationship Between Paget's Disease of Bone and Hyperparathyroidism?Cutaneous Vasculitis in Children and Adults: Associated Diseases and Etiologic Factors in 303 PatientsOccupational and environmental exposure to lead and Paget's disease of boneParathyroid function in paget's disease of boneHormonale Osteopathien im ErwachsenenalterHormonale Osteopathien im ErwachsenenalterPaget's Disease of BoneEffectiveness of parathyroid hormone, calcitonin and phosphate on bone cells in Paget's diseaseDie Pagetsche KnochenerkrankungReferencesPrimary hyperparathyroidism with osteosclerosis and calcification in articular cartilageHYPERPARATHYROIDISM ASSOCIATED WITH PAGET'S DISEASE*NORMAN N. KOHN, M.D., RALPH M. MYERSON, M.D., F.A.C.P.A clinical and pathological study of 63 functioning parathyroid tumorsGASTROINTESTINAL SYMPTOMS AS A CLUE TO THE DIAGNOSIS OF PRIMARY HYPERPARATHYROIDISM: A REVIEW OF 45 CASES*WALTER T. ST. GOAR, M.D.Fractures resulting from primary hyperparathyroidismÜBER HYPER-PARATHYREOIDISMUS EIN OPERIERTER FALL MIT SCHWEREN NIERENVERÄNDERUNGEN 1 July 1938Volume 12, Issue 1Page: 13-31KeywordsBoneHospital medicineHyperparathyroidismNeurofibromatosis type 1SurgeonsSurgery ePublished: 1 December 2008 Issue Published: 1 July 1938 PDF downloadLoading ...