Chapter 5 The Endocannabinoid System as A Target for Novel Anxiolytic and Antidepressant Drugs

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, L Hanŭs, Aviva Breuer et al. · Science · 1992 · 5.6K citations

Brain Constituent, Neurotransmitter, Cannabinoid Pharmacology +17

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

Raphael Mechoulam, Shimon Ben‐Shabat, L Hanŭs et al. · Biochemical Pharmacology · 1995 · 2.9K citations

Cannabis Use, Gastrointestinal Peptide Hormone, Functional Selectivity +6

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

Yehiel Gaoni, Raphael Mechoulam · Journal of the American Chemical Society · 1964 · 2.4K citations

Combinatorial Chemistry, Altmetrics, Partial Synthesis +14

2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain

Takayuki Sugiura, Shigeru Kondo, Akihiro Sukagawa et al. · Biochemical and Biophysical Research Communications · 1995 · 2.2K citations

Cannabis Use, Molecular Pharmacology, Functional Selectivity +9

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

Benjamin F. Cravatt, Dan K. Giang, Stephen P. Mayfield et al. · Nature · 1996 · 2.1K citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +7