Enhancement of productivity of recombinant α-amidating enzyme by low temperature culture

Mechanism of C-terminal amide formation by pituitary enzymes

A.F. Bradbury, M. D. A. FINNIE, D.G. Smyth · Nature · 1982 · 661 citations

Life Sciences, Biochemistry, Endocrinology +12

Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid.

Betty Eipper, Richard E. Mains, C C Glembotski · Proceedings of the National Academy of Sciences · 1983 · 366 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Factors affecting cell growth and monoclonal antibody production in stirred reactors

Shaul Reuveny, Daniel Uribe-Vélez, James D. Macmillan et al. · Journal of Immunological Methods · 1986 · 267 citations

Engineering, Biotechnology, Chemical Engineering +16

Fermentor temperature as a tool for control of high-density perfusion cultures of mammalian cells

Sandra Chuppa, Yeong-Shou Tsai, Sungjin Yoon et al. · Biotechnology and Bioengineering · 1997 · 134 citations

Engineering, Bioengineering, Biotechnology +16

Stabilization of Interferon Messenger RNA Activity by Treatment of Cells with Metabolic Inhibitors and Lowering of the Incubation Temperature

J Vilček, Edward A. Havell · Proceedings of the National Academy of Sciences · 1973 · 120 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10