Comparison of CYP3A Activities in a Subclone of Caco-2 Cells (TC7) and Human Intestine

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

Ismael J. Hidalgo, Thomas J. Raub, Ronald T. Borchardt · Gastroenterology · 1989 · 2.2K citations

Life Sciences, Cell Biology, Oncology +14

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

Ismael J. Hidalgo, Thomas J. Raub, Ronald T. Borchardt · Gastroenterology · 1989 · 1.1K citations

Life Sciences, Cell Biology, Oncology +14

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes.

Joseph C. Kolars, Phyllissa Schmiedlin‐Ren, John D. Schuetz et al. · Journal of Clinical Investigation · 1992 · 533 citations · Full text

Medicine, Molecular Biology, Pharmacology +14

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

Paul B. Watkins, Steven Wrighton, Erin G. Schuetz et al. · Journal of Clinical Investigation · 1987 · 483 citations · Full text

Medicine, Biochemistry, Molecular Biology +13

First-pass metabolism of cyclosporin by the gut

Joseph C. Kolars, Paul B. Watkins, Robert M. Merion et al. · The Lancet · 1991 · 428 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +11