Blood · 1997 · 391 citations · 145 references
Life SciencesCell BiologyImmunologyClinical ImmunologyImmunoregulationInflammationCytokine BiologyCytokine RegulationCytokine SignalingImmune-mediated Inflammatory DiseasesInflammatory Cell ResponsesInflammatory SignalingAnticytokine TherapyCytokine AntagonismInterleukin RegulationInterleukin-mediated InflammationT Helper 10 Cells
FIRST ISOLATED IN 1990, interleukin-11 (IL-11) has proven to be a fascinating cytokine with pleiotropic effects on multiple tissues. Initially characterized as a hematopoietic cytokine with thrombopoietic activity, IL-11 has now been shown to be expressed and have activity in multiple other tissues
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Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
Frédéric J. de Sauvage, Philip E. Hass, Susan D. Spencer et al. · Nature · 1994 · 1.3K citations
Medicine, Cell Biology, Hematology +11
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
Si Lok, Kenneth Kaushansky, Richard D. Holly et al. · Nature · 1994 · 1.1K citations