Histone H1-Mediated Transfection: Serum Inhibition Can Be Overcome by Ca2+ Ions

PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

Manfred Ogris, Silvia Brunner, Susanne Schüller et al. · Gene Therapy · 1999 · 1.2K citations

Pharmacy, Bioengineering, Pharmaceutics +16

Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery

Christian Plank, Karl Mechtler, Francis C. Szoka et al. · Human Gene Therapy · 1996 · 583 citations

Pharmacy, Immunology, Molecular Pharmaceutics +17

Detailed Analysis of Structures and Formulations of Cationic Lipids for Efficient Gene Transfer to the Lung

Edward R. Lee, John Marshall, Craig Siegel et al. · Human Gene Therapy · 1996 · 444 citations

Pharmacy, Molecular Biology, Pharmaceutics +17

Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA

J-P Yang, Leaf Huang · Gene Therapy · 1997 · 293 citations

Pharmacy, Biochemistry, Molecular Biology +12

A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA.

John G. Lewis, Kun Lin, A Kothavale et al. · Proceedings of the National Academy of Sciences · 1996 · 260 citations

Pharmacy, Biotechnology, Pharmaceutics +17