Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma

Convection-enhanced delivery of macromolecules in the brain.

R. Hunt Bobo, Douglas W. Laske, Aytaç Akbaşak et al. · Proceedings of the National Academy of Sciences · 1994 · 1.4K citations

Pharmacy, Neuroscience, Pharmaceutics +16

Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas

Henry Brem, Steven Piantadosi, P. C. Burger et al. · The Lancet · 1995 · 1.4K citations · Full text

Pharmacy, Oncology, Surgery +16

Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors

Douglas W. Laske, Richard J. Youle, Edward H. Oldfield · Nature Medicine · 1997 · 530 citations

Medicine, Neuroscience, Oncology +10

Descriptive epidemiology of primary brain and CNS tumors: Results fromthe Central Brain Tumor Registry of the United States, 1990-1994

Tanya Surawicz, Bridget J. McCarthy, Varant Kupelian et al. · Neuro-Oncology · 1999 · 445 citations

Medicine, Oncology, Cancer Epidemiology +13

Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion

Daniel Lieberman, Douglas W. Laske, Paul F. Morrison et al. · Journal of neurosurgery · 1995 · 346 citations

Pharmacy, Neuroscience, Pharmacology +13